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Yoko Shioda Selected Research

Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell)

1/2022New biomarker paves the way for a clinical trial for neurodegeneration in Langerhans cell histiocytosis.
3/2021Salvage therapy with 2-chlorodeoxyadenosine for refractory and relapsed pediatric Langerhans cell histiocytosis: an updated nationwide survey in Japan.
1/2021Long-term complications in uniformly treated paediatric Langerhans histiocytosis patients disclosed by 12 years of follow-up of the JLSG-96/02 studies.
10/2020Analysis of the BRAF and MAP2K1 mutations in patients with Langerhans cell histiocytosis in Japan.
1/2020Nationwide retrospective review of hematopoietic stem cell transplantation in children with refractory Langerhans cell histiocytosis.
1/2019Central diabetes insipidus in pediatric patients with Langerhans cell histiocytosis: Results from the JLSG-96/02 studies.
8/2018Intensification of induction therapy and prolongation of maintenance therapy did not improve the outcome of pediatric Langerhans cell histiocytosis with single-system multifocal bone lesions: results of the Japan Langerhans Cell Histiocytosis Study Group-02 Protocol Study.
1/2017Inflammatory serum cytokines and chemokines increase associated with the disease extent in pediatric Langerhans cell histiocytosis.
7/2016Intensified and prolonged therapy comprising cytarabine, vincristine and prednisolone improves outcome in patients with multisystem Langerhans cell histiocytosis: results of the Japan Langerhans Cell Histiocytosis Study Group-02 Protocol Study.
2/2015Follow-up of pediatric patients treated by IVIG for Langerhans cell histiocytosis (LCH)-related neurodegenerative CNS disease.
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Yoko Shioda Research Topics

Disease

13Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell)
01/2022 - 01/2011
9Neoplasms (Cancer)
11/2022 - 04/2004
4Neuroblastoma
01/2022 - 04/2004
4Neurogenic Diabetes Insipidus (Central Diabetes Insipidus)
01/2020 - 12/2011
4Down Syndrome (Down's Syndrome)
01/2020 - 05/2014
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2015 - 03/2014
2Juvenile Xanthogranuloma
04/2022 - 01/2021
2Acute Promyelocytic Leukemia
01/2022 - 01/2020
2Hypotension (Low Blood Pressure)
11/2021 - 11/2021
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2021 - 05/2014
1Cholestasis
03/2022
1Liver Cirrhosis (Hepatic Cirrhosis)
03/2022
1Disease Progression
11/2021
1Hyperaldosteronism (Conn Syndrome)
11/2021
1Kidney Diseases (Kidney Disease)
11/2021
1Hypertension (High Blood Pressure)
11/2021
1Shwachman-Diamond Syndrome
01/2021
1monosomy Chromosome 7
01/2021
1Seizures (Absence Seizure)
03/2020
1Sleepiness
03/2020
1Combined Pituitary Hormone Deficiency
01/2020
1Chronic Granulomatous Disease
01/2019
1Wilms Tumor (Wilm's Tumor)
10/2018
1Clear Cell Sarcoma
10/2018
1Sarcoma (Soft Tissue Sarcoma)
04/2016
1Non-Hodgkin Lymphoma (Lymphosarcoma)
03/2016
1Mucositis
03/2016
1Central Nervous System Diseases (CNS Diseases)
02/2015
1Spinal Cord Diseases
08/2014
1Immune System Diseases (Immune Disorders)
08/2014
1Rare Diseases (Rare Disease)
08/2014
1Subacute Combined Degeneration
08/2014
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2011
1Leukemia
01/2011
1Lymphoma (Lymphomas)
01/2011
1Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome)
10/2007
1Hepatolenticular Degeneration (Wilson's Disease)
10/2007
1Papilledema
07/2005
1Atrophy
07/2005
1Hemorrhage
07/2005

Drug/Important Bio-Agent (IBA)

3Cytarabine (Cytosar-U)FDA LinkGeneric
01/2021 - 07/2016
3ChemokinesIBA
01/2017 - 08/2014
3CytokinesIBA
01/2017 - 08/2014
2Cell-Free Nucleic AcidsIBA
11/2022 - 10/2018
2CladribineFDA LinkGeneric
04/2022 - 03/2021
2Arsenic Trioxide (Trisenox)FDA Link
01/2022 - 01/2020
2Mitogen-Activated Protein KinasesIBA
01/2021 - 10/2020
2Melphalan (Alkeran)FDA LinkGeneric
01/2021 - 01/2021
2Busulfan (Busulfex)FDA Link
03/2020 - 01/2019
2Prednisolone (Predate)FDA LinkGeneric
07/2016 - 07/2005
1DNA (Deoxyribonucleic Acid)IBA
11/2022
1Biomarkers (Surrogate Marker)IBA
01/2022
1olaparibIBA
01/2022
1Gemtuzumab (Mylotarg)FDA Link
01/2022
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2022
1Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2022
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2022
1Antihypertensive Agents (Antihypertensives)IBA
11/2021
1fludarabineIBA
01/2021
1Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
01/2021
1Levetiracetam (Keppra)FDA LinkGeneric
03/2020
1Clonazepam (Rivotril)FDA LinkGeneric
03/2020
1Growth Hormone (Somatotropin)IBA
01/2020
1Circulating Tumor DNAIBA
10/2018
1Vincristine (Oncovin)FDA LinkGeneric
07/2016
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
04/2016
1Intravenous Immunoglobulins (IVIG)FDA Link
02/2015
1OsteopontinIBA
12/2014
1Folic Acid (Vitamin M)FDA LinkGeneric
08/2014
1Methotrexate (Mexate)FDA LinkGeneric
08/2014
1Tyrosine Kinase InhibitorsIBA
03/2014
1Hormones (Hormone)IBA
12/2011
1Diphosphonates (Bisphosphonates)IBA
01/2011
1Retinaldehyde (Retinal)IBA
07/2005
1Tumor Biomarkers (Tumor Markers)IBA
05/2005

Therapy/Procedure

9Drug Therapy (Chemotherapy)
01/2021 - 04/2004
8Therapeutics
01/2022 - 01/2011
4Transplantation
01/2022 - 07/2005
4Hematopoietic Stem Cell Transplantation
01/2021 - 05/2014
2Liver Transplantation
03/2022 - 10/2007
2Nephrectomy
11/2021 - 11/2021
2Combined Modality Therapy
08/2020 - 10/2018
1Kidney Transplantation
11/2021
1Salvage Therapy
03/2021
1Induction Chemotherapy
08/2020
1Combination Drug Therapy (Combination Chemotherapy)
01/2019
1Homologous Transplantation
01/2019
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
08/2014
1Stem Cell Transplantation
05/2014
1Radiotherapy
04/2004